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KMID : 1084220150220030186
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Journal of Rheumatic Diseases
2015 Volume.22 No. 3 p.186 ~ p.189
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A Case of Varicelliform Zoster in a Patient Treated with Etanercept for Ankylosing Spondylitis
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Na Sun-Hee
Nam Eun-Young
Choe Pyeong-Gyun
Park Wan-Beom
Kim Nam-Joong
Oh Myoung-Don
Lee Eun-Young
Kim Nak-Hyun
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Abstract
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Tumor necrosis factor-α (TNF-α) inhibitors are increasingly used in treatment of inflammatory disorders because of their im-munomodulatory efficacy. Increased risk of infection is an adverse effect of anti-TNF-α therapy. The incidence rate and severity of herpes zoster is significantly higher in patients on anti-TNF-α therapy than in the general population. The clinical pre-sentation of varicella zoster virus infection is also often atypical in these patients. We experienced a patient who presented with a disseminated varicelliform rash while on etanercept therapy for ankylosing spondylitis.
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KEYWORD
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Herpes zoster, TNFR-Fc fusion protein, Ankylosing spondylitis
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